The rapidly increasing data on tumor genomics, coupled with information on drug response, have scientists all over the world building predictive models that might identify which patients are most likely to respond best to certain cancer drugs. But it doesn’t always work so well. Recent clinical trials employing such predictive models in patients with lung and breast cancers had to be suspended because the positive results that were seen in lab animals weren’t translating to people.
Dogs that develop cancer naturally may help scientists build better predictive models of cancer drug response. That’s the conclusion of a new study led by the Flint Animal Cancer Center at Colorado State University. Read more here.